BDBM261454 4-((1s,4s)-4-((4-fluorophenyl)sulfonyl)-4-(4-(perfluoropropan-2-yl)phenyl)cyclohexyl)thiomorpholine 1,1-dioxide::US9708253, 113

SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)N1CCS(=O)(=O)CC1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LQONCIVOELTUOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261454   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM261454(4-((1s,4s)-4-((4-fluorophenyl)sulfonyl)-4-(4-(perf...)
Affinity DataIC50: 75nMT: 2°CAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent