BDBM261502 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-carboxamide::US9708268, 5

SMILES Brc1ccc2NC(=O)CCc2c1

InChI Key InChIKey=MQWZSSIUHXNNTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 261502   

TargetInterleukin-17F(Human)
Innov17

US Patent
LigandPNGBDBM261502(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetInterleukin-17A(Human)
Innov17

US Patent
LigandPNGBDBM261502(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human CD4+ T cells were differentiated to TH17 cells as described in the presence or absence of various concentrations of compounds in a final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Innov17

US Patent
LigandPNGBDBM261502(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound binding to the human RORγ LBD was assessed using the Human RORγ Assay System (INDIGO Biosciences Inc.) as per manufacturer's i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent