BDBM261615 (S)-1-(2,2-diphenylacetyl)-4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine-2-carboxylic acid::US9708275, Compound 10::US9708275, Compound 7

SMILES OC(=O)[C@@H]1CN(CCCc2ccccc2)CCN1C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=LYHDFCWLNPUYTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261615   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261615((S)-1-(2,2-diphenylacetyl)-4-(3-methyl-1-phenyl-1H...)
Affinity DataIC50: 155nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261615((S)-1-(2,2-diphenylacetyl)-4-(3-methyl-1-phenyl-1H...)
Affinity DataIC50: 517nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent