BDBM261640 4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triethylsilyl)ethynyl)phenyl)thiazol-2-yl)benzamide::US9708279, 17

SMILES CC[Si](CC)(CC)C#Cc1cccc(c1)-c1csc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)n1

InChI Key InChIKey=KBKUMSXHFKGMLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261640   

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261640(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triet...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261640(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triet...)
Affinity DataIC50: 8.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent