BDBM261888 1-(2-Cyclopropyl-2-hydroxyethyl)-2-(9-ethyl-9H-carbazol-3-yl)-1H-benzimidazole-5-carboxylic acid::US9708311, 137

SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CC(O)C1CC1)C(O)=O

InChI Key InChIKey=RYUKCSMZZCGEIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261888   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM261888(1-(2-Cyclopropyl-2-hydroxyethyl)-2-(9-ethyl-9H-car...)
Affinity DataIC50: 18.6nMT: 2°CAssay Description:4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent