BDBM26240 N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]-2-(morpholin-4-yl)acetamide::pyrazolylpyrimidine derivative, 9a

SMILES COc1cncc(c1)-c1cc(NC(=O)CN2CCOCC2)nc(n1)-n1nc(C)cc1C

InChI Key InChIKey=CYCJQENBXNRINR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26240   

TargetAdenosine receptor A2a(Human)
Neurocrine Bioscience

LigandPNGBDBM26240(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypy...)
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Neurocrine Bioscience

LigandPNGBDBM26240(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypy...)
Affinity DataKi:  940nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed