BDBM26253 N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide::pyrazolylpyrimidine derivative, 16g

SMILES CN1CCN(CC1)c1cccc(n1)-c1cc(NC(C)=O)nc(n1)-n1nc(C)cc1C

InChI Key InChIKey=CQMWNSQCEMHNIW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26253   

TargetAdenosine receptor A2a(Human)
Neurocrine Bioscience

LigandPNGBDBM26253(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methyl...)
Affinity DataKi:  0.710nM ΔG°:  -12.3kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Neurocrine Bioscience

LigandPNGBDBM26253(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methyl...)
Affinity DataKi:  120nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed