BDBM26257 N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-hydroxypiperidin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide::pyrazolylpyrimidine derivative, 16k

SMILES CC(=O)Nc1cc(nc(n1)-n1nc(C)cc1C)-c1cccc(n1)N1CCC(O)CC1

InChI Key InChIKey=NOMOVVSYFDZGOW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26257   

TargetAdenosine receptor A2a(Human)
Neurocrine Bioscience

LigandPNGBDBM26257(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-hydrox...)
Affinity DataKi:  1.90nM ΔG°:  -11.8kcal/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Neurocrine Bioscience

LigandPNGBDBM26257(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-hydrox...)
Affinity DataKi:  470nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed