BDBM263708 US9714221, Example 45

SMILES Cc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)cc3)c3ccc(O)c(F)c3CCC2)c(F)c1

InChI Key InChIKey=GUJPHVNSSYDRIT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263708   

TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 263708BDBM263708(US9714221, Example 45)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetEstrogen receptor [Y537S](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 263708BDBM263708(US9714221, Example 45)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetEstrogen receptor [D538G](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 263708BDBM263708(US9714221, Example 45)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent