BDBM263971 2-(5-methyl-4-phenyl-1H-pyrazol- 1-yl)isonicotinic acid::US10173996, Example 36::US9604961, Example 36::US9714230, 36::US9908865, Example 36

SMILES Cc1c(cnn1-c1cc(ccn1)C(O)=O)-c1ccccc1

InChI Key InChIKey=DYVKRSMFVROHFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263971   

TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 263971BDBM263971(2-(5-methyl-4-phenyl-1H-pyrazol- 1-yl)isonicotinic...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 263971BDBM263971(2-(5-methyl-4-phenyl-1H-pyrazol- 1-yl)isonicotinic...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 263971BDBM263971(2-(5-methyl-4-phenyl-1H-pyrazol- 1-yl)isonicotinic...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent