BDBM264018 2-[5-[(4-ethyl-3- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid::US10173996, Example 96::US9604961, Example 96::US9714230, 96::US9908865, Example 96

SMILES CCc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)cc1F

InChI Key InChIKey=INIXTIFIUFLZRZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264018   

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264018BDBM264018(2-[5-[(4-ethyl-3- fluorophenyl)methoxy]pyrazol-1- ...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264018BDBM264018(2-[5-[(4-ethyl-3- fluorophenyl)methoxy]pyrazol-1- ...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264018BDBM264018(2-[5-[(4-ethyl-3- fluorophenyl)methoxy]pyrazol-1- ...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent