BDBM264088 2-[3-[(4-fluoro-2- methylphenyl)methyl]-5- hydroxypyrazol-1-yl]pyridine-4- carboxylic acid::US10173996, Example 173::US9604961, Example 173::US9714230, 173::US9908865, Example 173

SMILES Cc1cc(F)ccc1Cc1cc(O)n(n1)-c1cc(ccn1)C(O)=O

InChI Key InChIKey=IMBKDDQOCYXZQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264088   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264088BDBM264088(2-[3-[(4-fluoro-2- methylphenyl)methyl]-5- hydroxy...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264088BDBM264088(2-[3-[(4-fluoro-2- methylphenyl)methyl]-5- hydroxy...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent