BDBM264405 US9714247, 127

SMILES NCCn1c2cc(Nc3ccc(F)cn3)ncc2cc(-c2c(F)cccc2F)c1=O

InChI Key InChIKey=HLHICHWQRZZBDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264405   

TargetTyrosine-protein kinase BTK(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264405(US9714247, 127)
Affinity DataIC50: 100nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetTyrosine-protein kinase Lyn(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264405(US9714247, 127)
Affinity DataIC50: 550nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264405(US9714247, 127)
Affinity DataIC50: 550nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent