BDBM264527 3'-[4-({(8R)-8-[3,5- bis(trifluoromethyl)phenyl]- 6-oxo-7-oxa-5- azaspiro[3.4]oct-5- yl}methyl)-2-[methyl (methylsulfonyl)amino] pyrimidin-5-yl}-4'- methoxy-2-methylbiphenyl- 4-carboxylic acid::US9717714, 14

SMILES COc1ccc(cc1-c1cnc(nc1CN1C(=O)O[C@H](c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C11CCC1)N(C)S(C)(=O)=O)-c1ccc(cc1C)C(O)=O

InChI Key InChIKey=AFRZDMHYGVMIAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264527   

TargetCholesteryl ester transfer protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM264527(3'-[4-({(8R)-8-[3,5- bis(trifluoromethyl)phenyl]- ...)
Affinity DataIC50: 561nMAssay Description:Transfer assays are performed in a 96-well v-bottom polypropylene plate. For the RTA using recombinant CETP (2% RTA), an assay cocktail is prepared w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent