BDBM264730 2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-4-methoxy-6- (2-trifluoromethoxy-phenyl)-3H-imidazo[4,5-c]pyridine::US9718820, Compound 2

SMILES COc1nc(cc2nc([nH]c12)-c1c(Cl)c(nn1C)C(C)(C)C)-c1ccccc1C(F)(F)F

InChI Key InChIKey=NWHYESYIRRYBBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264730   

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM264730(2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)...)
Affinity DataIC50: 13nMT: 2°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent