BDBM26625 (5Z)-5-{[4-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 3a

SMILES OC1=NC(=O)C(S1)=Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GHXXZGKRRQQPIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26625   

TargetSerine/threonine-protein kinase pim-2(Human)
Medical University of South Carolina

LigandPNGBDBM26625((5Z)-5-{[4-(trifluoromethyl)phenyl]methylidene}-1,...)
Affinity DataIC50: 80nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Medical University of South Carolina

LigandPNGBDBM26625((5Z)-5-{[4-(trifluoromethyl)phenyl]methylidene}-1,...)
Affinity DataIC50: 330nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed