BDBM26758 2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]carbamate::bisarylimidazole derivative, 17

SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1

InChI Key InChIKey=LHAHTHILLRCRBM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26758   

TargetFatty-acid amide hydrolase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM26758(2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM26758(2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...)
Affinity DataIC50: 2nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM26758(2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...)
Affinity DataIC50: 2nMpH: 9.0 T: 2°CAssay Description:FAAH Inhibition Assay [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed