BDBM268505 N-(6-cyclopropyl-7-(01S,2S,5S)-6,6-dimethylbicyclo[3.1.1]-heptan-2-yl)methoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)azetidine-1-sulfonamide)::US9550775, 30::US9550775, 85

SMILES CC1(C)[C@@H]2C[C@H]1[C@@H](COc1cc3nnc(NS(=O)(=O)N4CCC4)n3cc1C1CC1)CC2

InChI Key InChIKey=RCPXFVHAVBREEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268505   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268505(N-(6-cyclopropyl-7-(01S,2S,5S)-6,6-dimethylbicyclo...)
Affinity DataIC50: 6.75nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268505(N-(6-cyclopropyl-7-(01S,2S,5S)-6,6-dimethylbicyclo...)
Affinity DataIC50: 7nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent