BDBM268993 US9718825, Example 436

SMILES O=S(=O)(Nc1ccc(-c2nc(N3CC(O)C3)c3cn[nH]c3n2)cc1F)c1cc(Cl)ccc1F

InChI Key InChIKey=ULPGKYXIFOTBLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268993   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 268993BDBM268993(US9718825, Example 436)
Affinity DataIC50: 130nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent