BDBM269089 2-Chloro-N-[2-fluoro-4-(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-phenyl]-5-methoxy-benzenesulfonamide::US9718825, Example 533

SMILES COc1ccc(Cl)c(c1)S(=O)(=O)Nc1ccc(cc1F)-c1ncc2c(C)n[nH]c2n1

InChI Key InChIKey=FMKJPHQRSKHQGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269089   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM269089(2-Chloro-N-[2-fluoro-4-(3-methyl-1H-pyrazolo[3,4-d...)
Affinity DataIC50: 1.40nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent