BDBM269448 (E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-1,3,4- oxadiazol-2- yl)vinyl)phenoxy)benzo [b]thiophen-6-ol::US10058534, 103

SMILES CCCc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccccc3C(C)C)cc2)o1

InChI Key InChIKey=GHWAJDYUYDORMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269448   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269448((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-1,3,...)
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269448((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-1,3,...)
Affinity DataIC50: 12nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent