BDBM269458 (E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo [b]thiophen-3- yl)oxy)benzylidene) butanoic acid::US10058534, 113

SMILES CC\C(=C/c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C(C)C)cc1)C(O)=O

InChI Key InChIKey=BARZCAWLKLVINJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269458   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269458((E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269458((E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...)
Affinity DataIC50: 62nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent