BDBM26959 4-aminoquinazoline derivative, 7b::N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]-5-methylquinazolin-4-amine

SMILES Cc1cccc2nc(\C=C\c3ccc(Cl)cc3)nc(NCCCCCCN)c12

InChI Key InChIKey=ACPNQYXVIVYUHR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26959   

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26959(N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]...)
Affinity DataKi:  170nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26959(N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]...)
Affinity DataKi:  808nM ΔG°:  -8.31kcal/molepH: 7.8 T: 2°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed