BDBM26967 (1S,2S)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}cyclohexane-1,2-diamine::4-aminoquinazoline derivative, (rac)-7j

SMILES Cc1ccc2nc(\C=C\c3ccc(Cl)cc3)nc(N[C@H]3CCCC[C@@H]3N)c2c1

InChI Key InChIKey=ZUNZDGFZAQCHPE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26967   

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26967((1S,2S)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  180nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26967((1S,2S)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  538nM ΔG°:  -8.55kcal/molepH: 7.8 T: 2°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed