BDBM26973 (1R,2S)-2-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquinazolin-4-yl}amino)cyclohexane-1-guanidine::4-aminoquinazoline derivative, (rac)-9c

SMILES [#6]-c1ccc2nc(-[#6]=[#6]-c3ccc(Cl)cc3)nc(-[#7]-[#6@H]-3-[#6]-[#6]-[#6]-[#6]-[#6@H]-3\[#7]=[#6](\[#7])-[#7])c2c1

InChI Key InChIKey=AOBZFFGDKGPTKO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26973   

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26973((1R,2S)-2-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-me...)
Affinity DataKi:  43nM ΔG°:  -10.0kcal/molepH: 7.8 T: 2°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26973((1R,2S)-2-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-me...)
Affinity DataKi:  220nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed