BDBM26977 2-benzoylquinazoline analogue, (1S, 2R)-17::N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-6-methylquinazolin-2-yl)-4-chlorobenzamide

SMILES [#6]-c1ccc2nc(-[#7]-[#6](=O)-c3ccc(Cl)cc3)nc(-[#7]-[#6@@H]-3-[#6]-[#6]-[#6]-[#6]-[#6@@H]-3\[#7]=[#6](/[#7])-[#7])c2c1

InChI Key InChIKey=WHUVYEIPFCHZOF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26977   

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26977(N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-...)
Affinity DataKi:  140nM ΔG°:  -9.34kcal/molepH: 7.8 T: 2°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-...)
Affinity DataKi:  270nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-...)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-...)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(N-(4-{[(1R,2S)-2-carbamimidamidocyclohexyl]amino}-...)
Affinity DataKi:  3.60E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed