BDBM270279 (2S,3R)-3-(3-(((S)-1-(2,5-bis(trifluoromethyl)benzyl)piperidin-3-yl)oxy)phenyl)-3-cyclopropyl-2-methylpropanoic acid::US10059667, Example 1::US10059667, Example 29
SMILES C[C@@H]([C@@H](C1CC1)c1cccc(O[C@H]2CCCN(Cc3cc(ccc3C(F)(F)F)C(F)(F)F)C2)c1)C(O)=O
InChI Key InChIKey=OGVDXOGTOYIYLA-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 270279
Affinity DataEC50: 1.90nMpH: 7.4 T: 2°CAssay Description:FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...More data for this Ligand-Target Pair
Affinity DataEC50: 51nMpH: 7.4 T: 2°CAssay Description:FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...More data for this Ligand-Target Pair
Affinity DataEC50: 89nMT: 2°CAssay Description:The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...More data for this Ligand-Target Pair
Affinity DataEC50: 711nMT: 2°CAssay Description:The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...More data for this Ligand-Target Pair