BDBM270487 US10059668, Example 51

SMILES O=C(NS(=O)(=O)C1CC1)\C=C\c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1

InChI Key InChIKey=MHWWSDSPWBDKRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270487   

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM270487(US10059668, Example 51)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent