BDBM272059 US10065945, Example 53

SMILES CCNC(=O)c1noc(NS(=O)(=O)c2ccc3CCN(Cc3c2)[C@H](C)c2cc(F)cc(F)c2)n1

InChI Key InChIKey=IUKFKCHBIQUOLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272059   

LigandPNGBDBM272059(US10065945, Example 53)
Affinity DataIC50: 7.10nMT: 2°CAssay Description:A solution of 1 M LiHMDS in THF (51.7 ml, 51.7 mmol) was added dropwise to a mixture of Intermediate 3 (7.5 g, 17.2 mmol) and 5-(tert-butyl)-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent