BDBM27219 (2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,2-a][1,2,4]triazin-2-yl]amino}butan-1-ol::(2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[2,1-f][1,2,4]triazin-2-yl]amino}butan-1-ol::imidazo[2,1-f]-1,2,4-triazine, 13

SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncc(C(C)C)n2n1

InChI Key InChIKey=ITFLOJJAVYXCTM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 27219   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 320nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed