BDBM272570 US10065967, Example 34

SMILES C[C@@H](N1Cc2cc3c(NC(C)=O)n[nH]c3cc2NC1=O)c1ccccc1

InChI Key InChIKey=JXHQSRKXFQZMFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272570   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272570(US10065967, Example 34)
Affinity DataIC50: 2.30nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent