BDBM273226 5-Amino-3-[(2R,3S,5S)-3-(1-hydroxy-1-methyl-ethyl)-5-[(1S)-1-hydroxypropyl]tetrahydrofuran-2-yl]-6H-thiazolo[4,5-d]pyrimidine-2,7-dione::US10065973, Example 20

SMILES CC[C@H](O)[C@@H]1C[C@H]([C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O)C(C)(C)O

InChI Key InChIKey=ARPUEIREOIOLGF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273226   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM273226(5-Amino-3-[(2R,3S,5S)-3-(1-hydroxy-1-methyl-ethyl)...)
Affinity DataEC50:  3.00E+3nMAssay Description:HEK293-Blue-hTLR7 cells were incubated at a density of 250,000-450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Modif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent