BDBM274350 US95556117, Example 14,4-Chloro-1H-indole-5-carboxylicacid [1-(6-chloro-pyridin-3-yl)-4,4-difluoro-cyclohexylmethyl]-amide

SMILES FC1(F)CCC(CNC(=O)c2ccc3[nH]ccc3c2Cl)(CC1)c1ccc(Cl)nc1

InChI Key InChIKey=HHSAZHDBUOAOSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274350   

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM274350(US95556117, Example 14,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 4.5nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent