BDBM274391 US95556117, Example 55,4-Chloro-7-(3-methoxy-propyl)-1H-indole-5-carboxylic acid (4,4-difluoro-1-hydroxy-cyclohexylmethyl)-amide

SMILES COCCCc1cc(C(=O)NCC2(O)CCC(F)(F)CC2)c(Cl)c2cc[nH]c12

InChI Key InChIKey=KLITUQALDUERKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274391   

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM274391(US95556117, Example 55,4-Chloro-7-(3-methoxy-propy...)
Affinity DataIC50: 6.70nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent