BDBM274397 US95556117, Example 61,4-Chloro-7-methyl-1H-indole-5-carboxylic acid [4,4-difluoro-1-(2-methyl-pyrimidin-5-yl)-cyclohexylmethyl]-amide

SMILES Cc1ncc(cn1)C1(CNC(=O)c2cc(C)c3[nH]ccc3c2Cl)CCC(F)(F)CC1

InChI Key InChIKey=MFSDVFGCMIMOLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274397   

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM274397(US95556117, Example 61,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 4nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent