BDBM274954 US9556188, Compound 30a

SMILES NC(=O)c1c2NCC3CN(CC[C@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C

InChI Key InChIKey=STKAJAXFRAFMLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274954   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM274954(US9556188, Compound 30a)
Affinity DataIC50: 0.660nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent