BDBM27537 4-[(3-{[4-(ethanesulfonyl)-1,4-diazepan-1-yl]carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1-one::Homopiperazine analogue, 18

SMILES CCS(=O)(=O)N1CCCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1

InChI Key InChIKey=BGVHHYHIASFHBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27537   

TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27537BDBM27537(4-[(3-{[4-(ethanesulfonyl)-1,4-diazepan-1-yl]carbo...)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed