BDBM275650 US9884814, Compound 261

SMILES COc1cc(CNC(=O)[C@@H](CC2CCCCC2)NC(=N)NC(=O)Cc2c(F)cc(F)cc2F)ccc1F

InChI Key InChIKey=XQJUWWVVWIHTOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275650   

TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM275650(US9884814, Compound 261)
Affinity DataIC50: 57nMpH: 5.5 T: 2°CAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent