BDBM275847 5-chloro-4-((5-chloro- 6-(2,2,3,3-tetrafluoro- propoxy)pyridin- 3-yl)oxy)-2-fluoro- N-(pyrrolidin-1- ylsulfonyl)benzamide::US10071957, Example 66

SMILES FC(F)C(F)(F)COc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=O)(=O)N2CCCC2)cc1Cl

InChI Key InChIKey=LYTKWPWNUUHGBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275847   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM275847(5-chloro-4-((5-chloro- 6-(2,2,3,3-tetrafluoro- pro...)
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent