BDBM27585 (Z)-alkene compound, 8::2-(4-{3-chloro-4-[(4Z)-5-(2-chloro-4-methylphenyl)hex-4-enamido]phenyl}phenoxy)acetic acid

SMILES C\C(=C\CCC(=O)Nc1ccc(cc1Cl)-c1ccc(OCC(O)=O)cc1)c1ccc(C)cc1Cl

InChI Key InChIKey=JGEXIGKIMXNLEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27585   

TargetGag-Pol polyprotein [588-1027](HIV-1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27585(2-(4-{3-chloro-4-[(4Z)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27585(2-(4-{3-chloro-4-[(4Z)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 785nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed