BDBM275961 US10071974, Example 72::US10071974, Example 73::US10071974, Example 74

SMILES CN(C(=O)C1CNCCOC1)C(C)(C)c2noc3c(Cl)cccc23

InChI Key InChIKey=QCICHSDBUXOUMR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 275961   

TargetSomatostatin receptor type 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275961(US10071974, Example 74 | US10071974, Example 73 | ...)
Affinity DataEC50:  8.40nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275961(US10071974, Example 74 | US10071974, Example 73 | ...)
Affinity DataEC50:  17.3nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275961(US10071974, Example 74 | US10071974, Example 73 | ...)
Affinity DataEC50:  1.19E+3nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent