BDBM27598 2-{[1-(2-chloro-4-methylphenyl)-4-methyl-1H-imidazol-2-yl]sulfanyl}-N-(2-chlorophenyl)acetamide::imidazolyl compound, 36

SMILES Cc1cn(c(SCC(=O)Nc2ccccc2Cl)n1)-c1ccc(C)cc1Cl

InChI Key InChIKey=TYHSHNHVWHLUBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27598   

TargetGag-Pol polyprotein [588-1027](HIV-1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27598(2-{[1-(2-chloro-4-methylphenyl)-4-methyl-1H-imidaz...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27598(2-{[1-(2-chloro-4-methylphenyl)-4-methyl-1H-imidaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed