BDBM276806 WO2011044181, Example 103

SMILES CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(Nc2cccc3OC(F)(F)Oc23)ccc1F

InChI Key InChIKey=HAAGHIKJWMPFPY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 276806   

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandPNGBDBM276806(WO2011044181, Example 103)
Affinity DataKi:  42nMpH: 5.0Assay Description:The following reagents were used in this assay. Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent