BDBM2770 3,3-Dibromo-4,4-dimethoxy-5,5-bis(methoxycarbonyl)-1,1-diphenyl-1,6-heptadiene::Alkenyldiarylmethane (ADAM) 11a::Alkenyldiarylmethanes (ADAM) 11a::methyl 3-bromo-5-{1-[3-bromo-4-methoxy-5-(methoxycarbonyl)phenyl]hepta-1,6-dien-1-yl}-2-methoxybenzoate

SMILES [#6]-[#8]-[#6](=O)-c1cc(cc(Br)c1-[#8]-[#6])-[#6](=[#6]/[#6]-[#6]-[#6]-[#6]=[#6])\c1cc(Br)c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]

InChI Key InChIKey=NZLQCPJMVKGKRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2770   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2770(3,3-Dibromo-4,4-dimethoxy-5,5-bis(methoxycarbonyl)...)
Affinity DataIC50: 9.90E+4nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM2770(3,3-Dibromo-4,4-dimethoxy-5,5-bis(methoxycarbonyl)...)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed