BDBM27716 4-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)phthalazin-1(2H)-one::4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2H-phthalazin-1-one::4-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl]-1,2-dihydrophthalazin-1-one::CHEMBL425201::phthalazinone analogue, 9a
SMILES O=c1[nH]nc(CCCCN2CCC(=CC2)c2ccccc2)c2ccccc12
InChI Key InChIKey=LIUHMYXLEFZHEQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27716
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:In vitro inhibitory concentration against Poly(ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 90nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair