BDBM2772 1,1-Bis[3-bromo-4-methoxy-5-(methoxycarbonyl)phenyl]-5-phenyl-1-pentene::Alkenyldiarylmethane (ADAM) 13a::Alkenyldiarylmethanes (ADAM) 13a

SMILES [#6]-[#8]-[#6](=O)-c1cc(cc(Br)c1-[#8]-[#6])-[#6](=[#6]/[#6]-[#6]-[#6]-c1ccccc1)\c1cc(Br)c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]

InChI Key InChIKey=WIQGQDRHNLNRCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2772   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2772(1,1-Bis[3-bromo-4-methoxy-5-(methoxycarbonyl)pheny...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM2772(1,1-Bis[3-bromo-4-methoxy-5-(methoxycarbonyl)pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed