BDBM27799 2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydro-1H-indol-6-yl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-6-fluorobenzamide::CHEMBL461876::pyrrolo[2,3-d]pyrimidine deriv., 23
SMILES COc1cc2CCN(C(=O)CN(C)C)c2cc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2cc[nH]c2n1
InChI Key InChIKey=WHVFDYQCAMPLMS-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27799
Affinity DataIC50: 1nMpH: 7.5 T: 22°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...More data for this Ligand-Target Pair