BDBM278552 (2E)-3-(1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(1-methoxycyclobutyl)-1,2-oxazol-4-yl]carbonyl}-3-methyl-1H-indol-4-yl]prop-2-enoic acid ::US10040791, Example 14
SMILES COC1(CCC1)c1onc(c1C(=O)n1cc(C)c2c(\C=C\C(O)=O)cccc12)-c1c(F)cc(Cl)cc1Cl
InChI Key InChIKey=HCJBIQJBHNAGCT-BQYQJAHWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 278552
Affinity DataIC50: 110nMpH: 7.5 T: 25°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.5 T: 25°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair