BDBM278844 2-[(1S,4S)- or (1R,4R)- 2,5-diazabicyclo[2.2.2] oct-2-yl]-N-[3- (difluoromethyl)-1- methyl-1H-pyrazol-4- yl]thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 23
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2csc3ncc(nc23)N2C[C@H]3CC[C@@H]2CN3)c(n1)C(F)F
InChI Key InChIKey=AIVGSRGEBPQQMX-DHTOPLTISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278844
Affinity DataIC50: 1nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair