BDBM278849 N-(3-cyano-1-methyl- 1H-pyrazol-4-yl)-2- (1,4-diazepan-1- yl)thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 28
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2csc3ncc(nc23)N2CCCNCC2)c(n1)C#N
InChI Key InChIKey=FRCZEZFUXNLPQH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278849
Affinity DataIC50: 26nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair